Lamellar introduces its LAMELLASOME technology for the safe and effective delivery of nucleic acids

Released: Monday 29th October 2018

Glasgow, UK – 29 October 2018 - Lamellar Biomedical Limited (Lamellar), an innovative biotechnology company, pioneering new approaches for the safe and effective transfer of functional nucleic acids, announces that Dr Alec McLean ,CEO, Dr Lynsey Howard (Head of Preclinical) and Steven Porteous (Head of Clinical and Regulatory) will be attending BIO-Europe 2018 in Copenhagen to introduce potential partners and investors to its cutting-edge LAMELLASOME™ technology.

Lamellar believes that its LAMELLASOME™ technology will play a key role in realising the potential of many of the nucleic acids in development, including mRNAs, siRNAs, DNA, miRs and plasmids, potentially revolutionising the treatment of many rare and intractable diseases.

Lamellar’s LAMELLASOME™ technology has been shown to deliver functional nucleic acids to a range of cell types including macrophages, human pulmonary fibroblasts and human dendritic cells. Crucially, all transfected cells types demonstrate very high cell viability and maintenance of cell phenotype/ function. Lamellar’s LAMELLASOME™ technology is entirely novel and does not utilise viral vectors or cationic or divalent ion-associated liposomes.

BIO-Europe is Europe's largest life science partnering conference serving the global biotechnology industry and takes place 5-7 November 2018. The conference attracts leading dealmakers from biotech, pharma and finance along with the most exciting emerging biotech and pharma companies.

For further information, please contact:

Lamellar Biomedical

Dr Alec McLean
+44 (0) 7494 897 377

Citigate Dewe Rogerson

David Dible/ Pip Batty/Shabnam Bashir

david.dible@citigatedewerogerson.com

About Lamellar Biomedical

Lamellar Biomedical Limited (Lamellar), is an innovative biotechnology company, pioneering new approaches for the transfer of functional nucleic acids. The Company’s unique and versatile LAMELLASOME™ platform has been designed for the safe and effective delivery of nucleic acid based therapeutics. Lamellar believes that its LAMELLASOME™ technology will play a key role in realising the potential of mRNAs, siRNAs, DNA, miRs, plasmids and other nucleic acids in development offering the potential to revolutionise the treatment of many rare and intractable diseases.

LAMELLASOME formulations have been shown to be effective in delivering functional nucleic acids to a range of cell types including macrophages, human pulmonary fibroblasts and human dendritic cells. The technology has also been used for the in vivo delivery of functional nucleic acids

Lamellar is developing its own pipeline of nucleic acid based therapeutics, the most advanced of which target Idiopathic Pulmonary Fibrosis and Cystic Fibrosis.

Founded in 2007, Lamellar is backed by both institutional and private investors, including Invesco, Scottish Enterprise, Barwell Plc, TRI Capital and has multiple research collaborations with world renowned institutions and universities

About LAMELLASOME™

LAMELLASOME™ technology comprises synthetic lipid vesicles with compositions based on human lamellar bodies/exosomes. LAMELLASOME™ technology represents a considerable advance in safe and effective non-viral transfection and is distinct from cationic and divalent liposomal approaches. LAMELLASOME™ formulations have an excellent preclinical safety profile, very high NOAEL (taken from inhalation toxicology) and excellent clinical safety profile.

Lamellar Biomedical can construct novel and bespoke LAMELLASOME™ formulations by removing, substituting and/or changing the proportions of their components and further improve their properties through manufacturing processes.

Lamellar Biomedical intends to tailor its LAMELLASOME™ technology to safely and effectively deliver nucleic acid based therapeutics to their target cells in order to optimise their functionality.

 

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